Biodegradable and bioactive porous polyurethanes scaffolds for bone tissue engineering

Biodegradable porous polyurethanes scaffold have themselves opportunities in service, including controlled degradation rate, no-toxic degradation products. However, polyurethanes are lack of bioactive groups, which limits their application. This review gives the common modification methods, surface functionalization and blending modification. In finally, the review puts forward to the bulk modification as a new method to enhance the bioactivity of polyurethanes.